cannabidiol (CBD)
Cannabidiol (CBD) is a phytocannabinoid with therapeutic properties that could be promising for numerous diseases. In some experimental models, CBD has anti-inflammatory, anticonvulsant, anti-nausea, anxiolytic and antipsychotic effects. The neuroprotective potential of CBD, based on the combination of its anti-inflammatory and antioxidant properties, is of particular interest and is currently the subject of intensive preclinical research for many neurodegenerative diseases. The neuroprotective effect appears to be based on an indirect effect on the endocannabinoid system by prolonging the effect of CB stimulants without directly interacting with the receptors. It also shows a positive effect on serotonin levels. The endocannabinoid system performs important biological functions in the central nervous system and in many other organs. The main function is to regulate the release of certain neurotransmitters, such as glutamate, noradrenaline or dopamine. In certain diseases, a specific influence on this signaling system, for example by inhibiting the breakdown of the body's own endocannabinoids (anandamide and 2-AG) or by supplying plant cannabinoids that bind to CB receptors, can be beneficial.
Possible therapeutic approaches are:
- Antiemetic: reduces nausea and vomiting.
- Anticonvulsant: reduces seizure activity.
- Antipsychotic: reduces psychotic disorders.
- Anti-inflammatory: fights inflammatory diseases.
- Antioxidant: fights neurodegenerative diseases.
- Anxiety-relieving: for anxiety disorders.
